Hantzsch Pyrrole Synthesis: Three ways for Pyrrole preparation with examples and Retro-synthesis. Video
#HantzschPyrroleSynthesis, #Pyrrolepreparation, #Pyrrole, #heterocyclicchemistry,
In this lecture, I have discussed the Hantzsch pyrrole synthesis. this method is associated with pyrrole preparation from alpha-amino ketone and alpha halo-carbonyl under basic condition. This method has few draw backs like self condensation etc. which was eliminated following three methods where slow regeneration of the alpha-aminoketone was achieved from some parent precursors. Additionally, I have discussed about the side products of this reaction with complete mechanistic justification. There are some related videos in my channel. I request the audience to go through them. Links are provided below.
For "Pyrrole preparation from Muccic acid and Furan: Complete mechanistic description." please click on the link "https://youtu.be/XEN7EAq3KMk"
For "Paal-Knorr Synthesis of Pyrrole: Complete mechanistic description." please click on the link "https://youtu.be/9gk6PvB3be4"
For "Preparation of pyridine: 1,5-dicarbonyl compounds and ammonia followed by aromatization." please click on the link "https://youtu.be/bQHT8xfng0M"
For "Aromatic electrophilic substitution on Five member heterocycles: Complete mechanistic description." please click on the link "https://youtu.be/EGnPC6cyJzY"
For "Knoor Method for pyrrole preparation: Three different methods with mechanism and retro-synthesis." please click on the link "https://youtu.be/p_LmsXC0feg"
For "Hantzsch Pyrrole Synthesis: Three ways for Pyrrole preparation with examples and Retro-synthesis." please click on the link "https://youtu.be/vRb_s7_kCvI"
For "Preparation and Restrosynthetic of 1,4 dicarbonyl compounds: for five-member heterocycle preparation" please click on the link "https://youtu.be/XvVRcRzUf1A"
For "Feist–Benary synthesis of Furan: From 1,3-dicarbonyl compounds and alpha-halo ketone in basic medium" please click on the link "https://youtu.be/JgGdwOcbFyY"
For "Paal-Knorr synthesis of Furan: From 1-4-dicarbonyl compounds." please click on the link "https://youtu.be/ZYhKdLd676Y"
For "Hinsberg Synthesis of Thiophene: Application of Stobbe Condensation Reaction (Lecture 3)." please click on the link "https://youtu.be/CW1sFyQuIxM"
For "Pyrrole preparation from Muccic acid and Furan: Complete mechanistic description." please click on the link "https://youtu.be/XEN7EAq3KMk"
For "Paal-Knorr Synthesis of Pyrrole: Complete mechanistic description." please click on the link "https://youtu.be/9gk6PvB3be4"
For "Decarboxylation of five Heterocycles: Complete mechanistic description and role of Resonance energy." please click on the link "https://youtu.be/kUKenWhFhbA"
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