Williamson Ether synthesis (Part 2): Limitation and Preparation of Cyclic Ethers (epoxide). Video
In this video, I have discussed the rest part missed in my previous video i.e. the limitation of this process and cyclic ether (epoxide) preparation procedure. Elimination becomes dominant when the alkyl halide is tertiary. Epoxide preparation from halohydrins is especially advantageous as the halohydrins are liquid at room temperature but the epoxide is gaseous. I have provided the link for the previous video and some of the related videos. Audiences are requested to watch them.
For "Williamson Ether Synthesis (part 1): Basic Concept and Complete Mechanistic Description." please click on the link "https://youtu.be/Qmikpv3NbGc"
For "Substitution Reaction (part 1): Basic concept." please click on the link "https://youtu.be/zGuTKXGQ_Zo"
For "SN1 (substitution nucleophilic uni-molecular): Basic concept of Substitution Reaction (part 2)." please click on the link "https://youtu.be/Ffq704NVz4c"
For "B-Strain or Back Strain in SN1 (substitution nucleophilic unimolecular) Reaction." please click on the link "https://youtu.be/maUV7FZg6p0"
For "I-strain or Internal Strain in SN1 (substitution nucleophilic unimolecular) Reaction." please click on the link "https://youtu.be/yQE6cbRzu1c"
For "SN2 (substitution nucleophilic bimolecular), Substitution Reaction (part 3)." please click on the link "https://youtu.be/Le53CiC1H3U"
For "Nucleophilic Substitution Reaction (SN2) on alpha halo-ketone." please click on the link "https://youtu.be/2cUiXYZzUoQ"
For "Nucleophilicity or Nature of Nucleophile on Nucleophilic Substitution reaction." please click on the link "https://youtu.be/Uw8UxuZdUqw"
For "Nucleophilic addition to Unsaturated carbon acting as an electrophile." please click on the link "https://youtu.be/5YowVOa0XQI"
For "Nature of Leaving Group in Nucleophilic substitution Reaction." please click on the link "https://youtu.be/T_qjWHE4A5s"
For "Effect of solvent in Nucleophilic Substitution Reaction" please click on the link "https://youtu.be/bUwuND3XaFo"
For "Epoxidation of alkene by peroxy acid (like m-CPBA): Basic concept & complete mechanism with examples" please click on the link "https://youtu.be/GJVtN4ZNmXk"
For "Epoxidation of ฮฑ,ฮฒ-unsaturated carbonyl compounds using hydrogen peroxide and alkali." please click on the link "https://youtu.be/AH1Q5n1uNIk"
For "Epoxide ring opening in acid, base & neutral (Lewis acid) medium: basic concept & reaction mechanism" please click on the link "https://youtu.be/CCt-OnQZByQ"
For "Contribution of Thrope-Ingold effect for Lactone stability & Epoxide preparation: complete mechanism" please click on the link "https://youtu.be/tShEpbUe3xY"
For "Corey-Chaykovsky reaction: preparation of epoxide using sulfur ylide: basic concept and mechanism." please click on the link "https://youtu.be/mAKT7y2F7Wc"
For "Williamson Ether synthesis (Part 2): Limitation and Preparation of Cyclic Ethers (epoxide)." please click on the link "https://youtu.be/Qmikpv3NbGc"
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